Tactical Medicine News Blog

Comparison of IM Midazolam, Olanzapine, Ziprasidone and Haloperidol for Behavioral Control

Posted by Marco Torres on

Background: Emergency providers frequently care for agitated patients ranging from restlessness to verbally and physically aggressive. Agitation is a symptom, not a diagnosis and these patients require careful evaluation to rule in or out serious medical conditions. Unfortunately, the agitation itself often obstructs this evaluation and places the patient, other patients and staff at risk. While verbal de-escalation can be effective in select cases, administration of medications for behavioral control is often required. Numerous medications are available for this indication, but the optimal approach is still unclear.

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Replace dolutegravir (Tivicay) with raltegravir (Isentress) for post-exposure prophylaxis

Posted by Curtis Geier, PharmD BCCCP on

Post-exposure prophylaxis (PEP) of patients who may have been exposed to HIV includes a combination HIV nucleoside analog reverse transcriptase inhibitor emtricitabine/tenofovir (Truvada) plus an integrase inhibitor. The CDC initially recommended the integrase inhibitor dolutegravir (Tivicay). However on May 18, 2018, the CDC placed an alert about the neural tube defect risk with dolutegravir.1 How does this change our ED practice?

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IV and/or Nebulized MgSO4 in Pediatric Asthma Exacerbations?

Posted by Marco Torres on

Background: Acute asthma exacerbations are a common presentation to pediatric emergency departments (EDs). Standard treatment with inhaled beta agonists and corticosteroids are often sufficient in mild asthma but can fall short in the treatment of moderate to severe exacerbations. Magnesium sulfate (MgSO4) has long been touted as an adjunct treatment due to its bronchodilatory properties (both in its intravenous (IV) and nebulized form). Despite its routine use, the evidence for its benefit is inconsistent, particularly in the adult population where the most recent large RCT demonstrated modest benefits (Goodacre 2013).

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ALiEM Cards: Maternal Cardiac Arrest

Posted by Jeremy Voros, MD on

Maternal cardiac arrest is a low-frequency, high-risk pregnancy complication with 2 lives at stake. Incidence is approximately 1 in 12,000 to 50,000 pregnancies with a greater than 40% mortality rate. Understanding physiologic changes of pregnancy and how to perform a perimortem cesarean section (resuscitative hysterotomy) are critical aspects of caring for maternal cardiac arrest. ALiEM Cards: Maternal Cardiac Arrest, written by Drs. Jeffrey Sakamoto, Collin Michels, Nikita Joshi, and Rebecca Bavolek, reviews the causes, management pearls, and summarizes the perimortem cesarean delivery.

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From One Medical Student to Another: 5 Tips for Research Success

Posted by Sara Capobianco on

One of the most challenging aspects of medical school is the sheer volume of information that must be absorbed in a short period. This can pose a problem for those interested in developing research skills and pursuing an independent project. As colleagues, we know that our inherent curiosity is satisfied by discovering new information as much as it is by learning clinical content. We believe that it is important to showcase our hard work through a formal research project, but there are systematic barriers to finding a research mentor and team. Although there are many resources to guide you on “how” to publish, in this post we give some basic tips and tricks, from one medical student to another, on how to get involved in research and find a project that best fits your goals.

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