Keep in mind that other drugs can interact with antidiabetic medications resulting in hypoglycemia. The following table applies only to single agent ingestion/administration.
| Drug Class | Examples | Hypoglycemic Potential |
| Insulins | Glargine, Aspart, Detemir | High |
| Sulfonylureas | Glyburide, Glipizide, Glimepiride | High |
| Meglitinides | Nateglinide, Repaglinide | High |
| Glucagon-Like Peptide-1 (GLP-1) Receptor Agonists | Exenatide, Albiglutide, Liraglutide | Low-Moderate |
| Alpha-glucosidase inhibitors | Acarbose, Miglitol | Low |
| Thiazolidinediones | Rosiglitazone, Piaglitazone | Low |
| Biguanides | Metformin | Low |
| Dipeptidyl Peptidase 4 (DPP-4) Inhibitors | Sitagliptin, Saxagliptin, Linagliptin | Low |
| Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitors | Canagliflozin | Low |
| Adapted from a University of Maryland Emergency Medicine (UMEM, @UMEmergencyMed) Educational Pearl. | ||
1.
Nelson L, Lewin N, Howland M Ann, Hoffman R, Goldfrank L, Flomenbaum N. Antidiabetics and Hypoglycemics. In: Goldfrank’s Toxicologic Emergencies. 9th ed. New York: Mcgraw-Hill; 2010:714-727.
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