Bleeding in general is bad. Bleeding while on anticoagulants is VERY bad. Dr. Rahul Patwari reviews the pathophysiology of coagulation, the various reversal agents, and treatment approaches we can use. In this five-part series where all videos are less than 10 minutes, Rahul goes from the basic physiology of coagulation all the way to the complex reasoning and approaches to reversing anticoagulants. These are worth a quick look and review.
Physiology of coagulation
The coagulation cascade
Reversing coumadin, part 1
Reversing coumadin, part 2
– use of prothrombin complex concentrates (PCC)
- Update, there is now a 4-factor PCC available in the U.S. now.
Reversing other anticoagulant drugs
- low molecular weight heparin
- dabigatran
- rivaroxaban
- thrombolytics
- aspirin
- clopidogrel
- abciximab
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