JJ 20 Outpatient Medications for COVID-19
February 14, 2022
In this Journal Jam podcast we dig deep into the science of FDA-approved outpatient medications for COVID with 3 critical appraisal masters: Dr. Andrew Morris,...
Anton Helman
The DisCoVeRy Trial: Remdesivir in COVID-19 – An Expensive Version of Tamiflu?
October 18, 2021
Background: Since the beginning of the pandemic, hundreds of trials have been performed looking at medications with the potential to be repurposed for use against...
Marco Torres
A COVID-19 Update that is Long Overdue
November 13, 2020
Background: There have been lots of trials sitting on my computer desktop awaiting my review, but like many of you time has been thin from...
COVID-19: An EBM Take
October 18, 2020
The Novel Coronavirus 2019, was first reported on in Wuhan, China in late December 2019. The outbreak was declared a public health emergency of international...
Remdesivir in Moderate COVID-19
September 10, 2020
Background: There are three randomized clinical trials now published on remdesivir in the treatment of COVID-19 pneumonia (RCT 1, RCT 2, & RCT 3). The...
COVID-19: Remdesivir RCT #3 (5d vs 10d)
June 2, 2020
Background: We have covered the two previous RCTs on remdesivir on REBEL EM (RCT #1 and RCT #2). In the first trial by Wang et...
REBEL Cast Ep83 – COVID-19 in the ICU, ECMO Early, & Steroids with Jeff Dellavolpe, MD
May 31, 2020
I am fortunate to work in a hospital system that is very forward thinking. We have a phenomenal relationship with our intensivists, and I have...
Remdesivir ACTT-1: Adaptive COVID-19 Treatment Trial Part 1
May 26, 2020
Background: The saga of Remdesivir for treatment of COVID-19 continues. We previously covered two studies of this drug on REBEL EM (Link is HERE &...
COVID-19: Two More Trials Just Published on Remdesivir
April 30, 2020
Background: Currently, there are no approved medications for the treatment of COVID-19, but, there are many investigational agents that have shown antiviral activity against SARS-CoV-2...