Your Cart ()
cload

GUARANTEED SAFE & SECURE CHECKOUT

Spend $99.99 to Unlock Free Shipping within CONUS.

Acido Tranexamico (TXA) Intramuscular IM vs IV / Tranexamic acid (TXA) Intramuscular IM vs IV

By EMS Solutions International April 14, 2023 0 comments

Tranexamic acid (TXA) Intramuscular IM vs IV / Tranexamic acid (TXA) Intramuscular IM vs  IV 

Leer tema relacionado 

Tema para ver con detenimiento y revisa, no creo sea concluyente, pero me llama la atención bastante 

Prehospital Tranexamic Acid for Severe Trauma. June 2023 

Conclusions: Among adults with major trauma and suspected trauma-induced coagulopathy who were being treated in advanced trauma systems, prehospital administration of tranexamic acid followed by an infusion over 8 hours did not result in a greater number of patients surviving with a favorable functional outcome at 6 months than placebo. (Funded by the Australian National Health and Medical Research Council and others; PATCH-Trauma ClinicalTrials.gov number, NCT02187120.).

https://pubmed.ncbi.nlm.nih.gov/37314244/

 "¡Dale la TXA a través de sus jeans!"

Espera, ¿IM TXA es una cosa?

➼ Aquí hay algunos antecedentes:

La administración intravenosa de ácido tranexámico (TXA) puede ser difícil en pacientes con hemorragia.

Su administración demora aproximadamente diez minutos, período durante el cual el paramédico debe permanecer con el paciente.

Eso provocará retrasos en el tratamiento de otros pacientes en una situación de víctimas en masa.

Ambos problemas podrían resolverse mediante el uso de TXA intramuscular en lugar de intravenoso.

➼ Haga una inmersión más profunda:

⁍ El ácido tranexámico (TXA) es un fármaco antifibrinolítico que reduce el sangrado al inhibir la descomposición enzimática de los coágulos sanguíneos de fibrina.

⁍ Sangrado quirúrgico: TXA se usa ampliamente para reducir el sangrado y la necesidad de transfusión de sangre en procedimientos quirúrgicos. Una revisión sistemática y un metanálisis en 2012 mostraron que TXA redujo la necesidad de una transfusión de sangre en un tercio.

⁍ Sangrado traumático: El tratamiento precoz es fundamental. El tratamiento dentro de las tres horas de la lesión reduce la muerte

⁍ Sangrado posparto: TXA redujo el riesgo de muerte por hemorragia en una quinta parte.

➼ Entonces, ¿es Intramuscular una mejor alternativa a IV?

‣ Después de la inyección intramuscular de TXA (que toma segundos), los niveles terapéuticos de TXA se alcanzan en aproximadamente 10 minutos.

Suena como un rotundo ¡SÍ!

Lea el estudio aquí:

"Give the TXA through their jeans!"


Wait, is IM TXA a thing?

➼ Here's some background:
Intravenous administration of Tranexamic acid (TXA) may be difficult in hemorrhaging patients.
It takes approximately ten minutes to administer, during which period the paramedic must remain with the patient.
That will cause delays in the treatment of other patients in a mass casualty situation.
Both problems could be solved by the use of intramuscular as opposed to intravenous TXA

➼ Take a Deeper Dive:
⁍ Tranexamic Acid (TXA) is an antifibrinolytic drug that reduces bleeding by inhibiting the enzymatic breakdown of fibrin blood clots.
⁍ Surgical bleeding: TXA is widely used to reduce bleeding and the need for blood transfusion in surgical procedures. A systematic review and meta-analysis in 2012 showed that TXA reduced the need for a blood transfusion by a third.
⁍ Traumatic bleeding: Early treatment is essential. Treatment within three h of injury reduces death
⁍ Postpartum bleeding: TXA reduced the risk of hemorrhage death by one-fifth.

➼ So, is Intramuscular a better alternative to IV?
‣ After intramuscular injection of TXA (which takes seconds), therapeutic TXA levels are achieved in about 10 min.

Sounds like a resounding YES!

Read the study here:
http://ow.ly/27pQ50NEbzg


Le puede interesar

Ácido Tranexámico ATX. (TRANEXAMIC ACID TXN) Beneficios en el Trauma con Shock Hemorrágico. EMSWORLD

https://emssolutionsint.blogspot.com/2014/12/acido-tranexamico-mejora-la-mortalidad.html


Tranexamic Acid for trauma-related hemorrhage TXA

https://emssolutionsint.blogspot.com/2014/12/txa-use-approved-for-nc-critical-care.html


TXA / ATX Acido Tranexámico en Pacientes con Trauma Pediátricos

https://emssolutionsint.blogspot.com/2021/06/txa-atx-acido-tranexamico-en-pacientes.html


Acido Tranexamico (TXA) Intramuscular IM vs IV / Tranexamic acid (TXA) Intramuscular IM vs IV 

https://emssolutionsint.blogspot.com/2023/04/tranexamic-acid-txa-intramuscular-im-vs.html




Older Post Newer Post

Newsletter

I agree to subscribe to updates from Shoptimized™

Categories

B. Dupont Purchased 2 minutes ago from Los Angeles, CA
2
C. Santos Purchased 2 minutes ago from Chicago, IL
5.11 FLEX TacMed Pouch
D. Kim Purchased 1 minute ago from Houston, TX
5.11 FLEX Tourniquet Pouch
E. García Purchased 1 minute ago from Phoenix, AZ
5.11 UCR TacReady Headrest Pouch
F. Müller Purchased 1 minute ago from Philadelphia, PA
Abdominal Aortic and Junctional Tourniquet-Stabilized (AAJT-S)
G. Rossi Purchased 1 minute ago from San Antonio, TX
Adjustable Flange Nasopharyngeal Airway
H. Martinez Purchased 1 minute ago from San Diego, CA
Adult Bag Valve Mask
J. López Purchased 2 minutes ago from Dallas, TX
Altama OTB Maritime Assault Boot - Low Height
K. Nowak Purchased 2 minutes ago from San Jose, CA
Altama OTB Maritime Assault Boot - Mid Height
L. Müller Purchased 1 minute ago from Austin, TX
AMBU Perfit ACE Adjustable Cervical Extrication Collar
M. Ivanova Purchased 2 minutes ago from Jacksonville, FL
Amphibious Trauma Kit
N. Andersen Purchased 1 minute ago from Fort Worth, TX
Army CLS Resupply Kit (CLS™)
O. Fischer Purchased 2 minutes ago from Columbus, OH
Backpack Accessory Pouch Kit - 4 Color
P. Bernard Purchased 1 minute ago from Charlotte, NC
Ballistic Soft Panel for Plate Carrier
S. Schmidt Purchased 1 minute ago from San Francisco, CA
Bandage Fill Kit
T. Kowalski Purchased 1 minute ago from Indianapolis, IN
Bandage Shears
X. Martinez Purchased 1 minute ago from Seattle, WA
Bard-Parker Safety Scalpel #10
Y. Ahmed Purchased 2 minutes ago from Denver, CO
Basic Field Surgical Airway Kit w/ET Tube
Z. Khan Purchased 1 minute ago from Washington, DC
Beacon Chest Seal - Occlusive/Non-Vented
A. Ali Purchased 1 minute ago from Boston, MA