PV Card: Acute Salicylate Toxicity

Sam Shaikh, DO on

aspirin pillsPatients with acute salicylate toxicity can rapidly decompensate and require clinicians to understand the pathophysiology of what is going on. First a respiratory alkalosis occurs with non-specific symptoms of vomiting and dizziness. Then an anion-gap metabolic acidosis also occurs with headache, tinnitus, and confusion. Below lists the core set of labs to obtain and treatment strategies by our stellar ALiEM-CORD Social Media and Digital Scholarship Fellow, Dr. Sam Shaikh.

aspirin pillsPatients with acute salicylate toxicity can rapidly decompensate and require clinicians to understand the pathophysiology of what is going on. First a respiratory alkalosis occurs with non-specific symptoms of vomiting and dizziness. Then an anion-gap metabolic acidosis also occurs with headache, tinnitus, and confusion. Below lists the core set of labs to obtain and treatment strategies by our stellar ALiEM-CORD Social Media and Digital Scholarship Fellow, Dr. Sam Shaikh.

PV Card: Acute Salicylate Toxicity

The card was updated 6/5/15 to the following card following post-publication expert peer review:


See other Paucis Verbis cards.

Author information

Sam Shaikh, DO

Sam Shaikh, DO

Editor, 60-Second Soapbox series
Assistant Clinical Professor, Rocky Vista University
Clinical Instructor, University of Colorado School of Medicine
2014-15 ALiEM-CORD Social Media and Digital Scholarship Fellow

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Tags: Tox & Medications

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