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Thanks for dropping by! We have curated an incredible collection of the best articles from the leading Emergency Medicine, Tactical Medicine, Prehospitial Medicine, Austere & Remote Medicine authors, as well as Survival Medicine gurus and many others!

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Tactical Medicine News

Tenecteplase vs Alteplase in Acute Ischemic Stroke

by Marco Torres
Jun 16, 2022
Background: At my shop we have changed wholesale to the use of tenecteplase over alteplase for acute ischemic stroke meeting criteria for thromboly...
Tactical Medicine News

Rebellion21: Stroke – Tiiii-ii-iiime is on Your Side, or is it? via George Willis, MD

In this 15-minute lecture from Rebellion in EM 2021, George Willis, MD discusses acute ischemic stroke and the evidence base for and against thromb...
Tactical Medicine News

Rebellion21: Alteplase for Stroke of Unknown Time of Onset

In this 9 minute video from day 2 of Rebellion in EM 2021, I go over the evidence for advanced imaging use in acute ischemic stroke of unknown time...
Tactical Medicine News

Tenecteplase for Thrombolysis of AIS?

Background: Alteplase has been the accepted thrombolytic for acute ischemic stroke (AIS) for 25 years. However, recent data has emerged regarding t...
Tactical Medicine News

REBEL Cast Ep92: Alteplase for Stroke of Unknown Time of Onset?

Background: Intravenous alteplase is the current standard care for treatment of acute ischemic stroke (AIS) despite active debate on the research s...
Tactical Medicine News

Thrombolysis in Acute Ischemic Stroke: Now We Have No Positive RCTs

Background: The scientific process in medicine is complicated. Obtaining high-quality data to guide management requires hypothesis formulation, dat...
Tactical Medicine News

Extending Systemic Thrombolysis to 4.5 – 9 Hours and Wake-Up Strokes Using Perfusion Imaging: A Meta-Analysis

Background Information: The administration of alteplase (tPA) in acute ischemic stroke (AIS) continues to remain a highly debated topic. As hospita...
Tactical Medicine News

REBEL Cast Ep72: Systemic Alteplase in Stroke Mimics is Safe?

Background: Currently, alteplase is the mainstay of treatment of acute ischemic stroke.  Advocates of alteplase suggest that the benefit of altepla...
Tactical Medicine News

EMU 365 Thrombolysis in Pulmonary Embolism with Amit Shah

The final EMU365 video from EMU2018 features Dr. Amit Shah who discusses decision making and dosing around the use of thrombolytics in PE in the co...
Tactical Medicine News

Extending the tPA Window to 4.5 – 9 Hours in Acute Ischemic Stroke (AIS)?

Background: No matter which side of the debate you sit on in regard to systemic thrombolysis in acute ischemic stroke (AIS), there is one truth: sy...
Tactical Medicine News

PRISMS Trial: Alteplase vs. Aspirin in Minor Stroke

Background: Despite serious concerns about the role of alteplase in the management of acute ischemic stroke including, but not limited to, signific...
Tactical Medicine News

BCE 74 Coding in the Scanner

In anticipation of EM Cases Episode 113 Diagnosis an Workup of Pulmonary Embolism with Dr. Kerstin DeWit and Dr. Eddy Lang, we have Dr. Peter Reard...
Tactical Medicine News

Tenecteplase versus Alteplase before Endovascular Therapy for Ischemic Stroke (EXTEND-IA TNK)

Background: Alteplase is a tissue plasminogen activator that is approved for use prior to thrombectomy in ischemic strokes with the goal of reperfu...
Tactical Medicine News

The ENCHANTED Trial: Is Low-Dose the Right Dose for Intravenous tPA in Acute Ischemic Stroke?

Background: Despite continued debate on the efficacy of alteplase (tPA), it currently remains one of the major interventions directed at patients p...
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