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CELOX™ Rapid Ribbon Hemostatic Z-Fold Gauze, 1 in. × 5 ft

(7 reviews)
$29.95
Packaging: MARCH Red Packaging
MARCH Red Packaging
Tactical Dark Green
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$29.95
PRODUCT INFORMATION
CELOX™ by Medtrade · Hemostatic Ribbon Gauze
CELOX™ Rapid Ribbon Hemostatic Z-Fold Gauze, 1 in. × 5 ft
CELOX Rapid in a strip one inch wide: 5 ft of Z-folded gauze coated with Chito-R™ chitosan granules that stick to wet tissue and seal the bleeding source with an adhesive gel. Medtrade built it for narrow entry wounds — bullet, blast fragment and stab injuries — in a low-profile pack that conceals easily, labeled for 60 seconds of firm compression.
evidence-based standard1 in. × 5 ft Z-fold60-second labeled holdChito-R™ chitosanFDA 510(k) cleared

Width decides what you can pack. A one-inch ribbon goes down a narrow wound track to the bleeding source, and the technique is the same as every other packing gauze.

The short answer
What it is
Chitosan-coated hemostatic packing ribbon, 1 in. × 5 ft, Z-folded, one sterile dressing per sealed pouch.
Use it for
Life-threatening bleeding from narrow entry wounds — bullet, blast fragment and stab injuries — that you can pack and compress, where a tourniquet cannot control the bleeding.
Hold pressure
Medtrade labels the Ribbon for 60 seconds of firm pressure, and longer if bleeding persists; the TCCC Guidelines set at least 3 minutes for any hemostatic dressing. Both are minimums: keep pressure on until the bleeding has stopped and the packing is secured.
Who carries it
Tactical operators, law enforcement, EMS and armed citizens who want a hemostatic small enough for a pocket or ankle kit.

At a glance

Active agent
Chito-R™ chitosan
Gauze
1 in. × 5 ft (2.5 cm × 1.5 m)
Format
Z-fold ribbon, sterile sealed pouch
Labeled hold
60 s, then until bleeding stops
Cold blood
Effective down to 56 °F (13 °C)
NSN
6510-01-623-9442
Manufacturer codes
FG08839041 · FG05839141
FDA
510(k) K110386
Packaging
Tactical Dark Green or MARCH red (RAMPART™)

12 things to know about CELOX Rapid Ribbon

What the narrow format is for, what the 60-second label means, and what the CELOX Rapid studies found.

  1. 01

    CELOX Rapid, one inch wide

    Medtrade describes the Ribbon as bringing all the benefits of CELOX Rapid Gauze in a 1-inch strip.3 The label calls it a hemostatic Z-fold gauze with Chito-R™ technology, one strip 1 in. × 5 ft (2.5 cm × 1.5 m).2

  2. 02

    Built for narrow wound tracks

    Medtrade designed the reduced size for narrow entry wounds such as bullet, blast fragment and stab injuries.3 The pack itself is low-profile and easily concealed.3

  3. 03

    How Chito-R works

    Chito-R™ activated chitosan granules stick to wet tissue in the wound and form an adhesive gel that seals it and stops the flow of blood.3 Medtrade describes CELOX chitosan as working independently of the body's clotting cascade.3

  4. 04

    The 60-second label

    Medtrade's instructions call for firm pressure directly on the wound for 60 seconds, and additional pressure until the bleeding stops if it persists.2 Medtrade's laboratory trials found the Ribbon stopped major arterial bleeding by coagulating the blood within 60 seconds.2

  5. 05

    How the label fits with TCCC

    The TCCC Guidelines set at least 3 minutes of direct pressure for every hemostatic dressing.1 The two figures do not compete — both are minimums. Neither one is a reason to take your hands off a wound that is still bleeding.

  6. 06

    Cold blood

    Medtrade's laboratory testing found the granules effective in blood temperatures down to 56 °F (13 °C).2

  7. 07

    FDA-cleared

    The Ribbon is FDA-cleared under 510(k) K110386, CELOX Rapid Gauze, cleared in May 2011 for temporary external use to control moderate to severe bleeding.4

  8. 08

    evidence-based standard

    CELOX Rapid Ribbon is evidence-based standard, alongside CELOX Rapid and Celox Gauze in the CELOX chitosan family. Combat Gauze remains the evidence-based hemostatic dressing of choice.1

  9. 09

    The CELOX Rapid evidence is mixed — read both studies

    The published animal studies tested 3 in. CELOX Rapid, the parent gauze. In 36 swine with no pressure held after packing, success was statistically the same for plain gauze, Combat Gauze and CELOX Rapid, and CELOX Rapid packed fastest with the least secondary blood loss.7 In 21 swine with a 3-minute hold, Combat Gauze held at one hour in every animal and CELOX Rapid in 60%.8

  10. 10

    Coagulopathy and prolonged care

    In coagulopathic swine, CELOX Rapid performed comparably to Combat Gauze;9 in a second coagulopathic study its re-bleed rate was 17% in both a junctional and a liver model, with no significant difference among the five agents tested.10 In a 24-hour junctional model, 60% of swine treated with CELOX Rapid survived, the same as Combat Gauze.11

  11. 11

    Shellfish allergy is rarely the issue

    The Ribbon contains chitosan from shellfish, and Medtrade reports that allergy studies show no adverse reaction to date.2 In a challenge study, ten volunteers with confirmed shellfish allergy tolerated a chitosan bandage without reaction.12 In a life-threatening bleed, a reported shellfish allergy is not a reason to withhold it.

  12. 12

    Two packaging options, one dressing

    Tactical Dark Green (FG08839041) and MARCH red, the pack made for Safeguard Medical's RAMPART™ color-coded system (FG05839141), are packaging choices only; the 1 in. × 5 ft Chito-R ribbon inside is the same, under NSN 6510-01-623-9442.3,5,6

How to pack CELOX Rapid Ribbon

Medtrade's instructions and the technique taught in TCCC, TECC and public bleeding-control courses, in order.

  1. 1
    Find the source. Expose the wound, identify the point of bleeding and apply direct pressure. Swab away excess blood where practical.2
  2. 2
    Open the pack. Tear it open, take out the Ribbon and take hold of one end of the Z-folded gauze.2
  3. 3
    Start with a tight wad. Make the first folds into a firm ball — the "power ball" — and press it directly onto the bleeding source.
  4. 4
    Pack to the source. Feed the unfolding Ribbon in tightly, keeping pressure on what is already packed. Fill every corner until the wound is filled above skin level; cut or tear off the excess.2
  5. 5
    Hold firm pressure. At least 60 seconds per the Celox label, or at least 3 minutes if you work under TCCC1,2 — and in every case until the bleeding has stopped.
  6. 6
    Lock it in. Secure the packing with a pressure bandage so pressure stays on the wound, and discard any unused Ribbon.2
  7. 7
    If it keeps bleeding, repack. Remove the packing and pack again with a fresh dressing, the same type or another hemostatic.1 Piling more gauze on top of a failed pack does not fix it.
  8. 8
    Hand it off. Get the casualty to a medical facility, tell the receiving team a chitosan hemostatic is in the wound, and show them the empty pack.2
Train before you need it. Packing a narrow track is a hands-on skill. Practice on a gunshot-wound packing trainer with inert gauze and keep your live Ribbon sealed for the casualty.

Where it fits

Use it for
  • Narrow entry wounds — bullet, blast fragment and stab injuries — with life-threatening bleeding3
  • Junctional wounds — groin and armpit — where a limb tourniquet cannot be applied1
  • Neck wounds, packed with care so the airway is not compressed; the lower neck above the collarbone can be packed
  • Deep limb wounds where a tourniquet is not possible, or as an adjunct when a trained provider converts a tourniquet1
Not for
  • The chest or abdomen — never pack into the chest or abdominal cavity2
  • Wounds you cannot compress — packing needs pressure to work2
  • Life-threatening limb bleeding a tourniquet can control — tourniquet first1
  • Wide, open cavities — a 3 in. gauze such as CELOX Rapid or Celox Gauze fills them faster
  • The eyes — keep the dressing away from the eyes2

The evidence

The studies behind the claims above. All animal studies tested 3 in. CELOX Rapid, the parent gauze.

Study Evidence type What was studied What it found
Waibel et al., Mil Med 2011 Human · safety challenge HemCon chitosan bandage applied to 10 volunteers with confirmed shellfish allergy All tolerated the bandage without reaction; no protein detected in the chitosan
Kunio et al., Am J Surg 2013 Animal · randomized CELOX Rapid (parent gauze) vs Combat Gauze vs plain gauze, femoral artery injury, 36 swine, no pressure held after packing Success not statistically different (12/12, 10/12, 10/12); secondary blood loss median 12.8 mL vs 31.9 mL vs 44.7 mL; packing 37.1 s vs 43.5 s vs 45.2 s
Johnson & Johnson, Am J Disaster Med 2019 Animal · randomized CELOX Rapid (parent gauze) vs Combat Gauze, 6 mm femoral artery injury, 21 swine, 3-minute hold plus simulated pressure dressing Initial hemostasis 70% vs 100%; 60% vs 100% at one hour — favored Combat Gauze
Gerling et al., J Trauma Acute Care Surg 2023 Animal · coagulopathy CELOX Rapid (parent gauze) and six other agents vs Combat Gauze, coagulopathic swine junctional injury Most agents, including CELOX Rapid, comparable to Combat Gauze
Patterson et al., PLoS One 2025 Animal · coagulopathy CELOX Rapid (parent gauze) and four other agents, femoral and liver injuries in 60 hemodiluted swine CELOX Rapid re-bleed 17% in both models; no significant difference in hemostasis, re-bleeding or survival among agents
Booms et al., Mil Med 2026 Animal · prolonged field care CELOX Rapid (parent gauze) and other dressings, fatal junctional femoral injury in swine, up to 24 hours CELOX Rapid survival 14.9 ± 12.4 h, 60% at 24 h — the same rate as Combat Gauze

Strongest to weakest: human studies, then animal studies, then laboratory studies. The two oldest swine studies reached different conclusions because they tested different things — one with no pressure held after packing, one with a 3-minute hold and a pressure dressing.

How it compares

How the Ribbon sits against the other packing gauzes a buyer weighs.

Celox Rapid Ribbon Celox Rapid Celox Gauze 10 ft Combat Gauze
Strip 1 in. × 5 ft Z-fold 3 in. × 5 ft Z-fold 3 in. × 10 ft Z-fold 3 in. × 4 yd (12 ft)
Active agent Chito-R™ chitosan granules Chito-R™ chitosan granules CELOX chitosan granules Kaolin (mineral)
Pressure hold 60 s labeled; TCCC at least 3 min 60 s labeled; TCCC at least 3 min 3 min labeled; TCCC at least 3 min TCCC at least 3 min
Built for Narrow entry wounds — bullet, blast fragment, stab Packable wounds, fast packing Large, deep cavities Packable wounds
evidence-based standard Yes Yes Yes Yes — hemostatic dressing of choice
Shellfish-derived Yes Yes Yes No

Celox labeled times come from Medtrade's instructions; the TCCC Guidelines set at least 3 minutes of direct pressure for any hemostatic dressing.1 Whatever the label, keep pressure on until the bleeding has stopped.

Build the system

The rest of the CELOX system, the alternatives, the bandage that holds the packing in, and trainers to practice on.

Free from MED-TAC
The Trauma Brief
MED-TAC's free trauma field guide, written by a physician and medical educator — what to do in the first minutes of a severe bleed, step by step.
Get the Brief ›

Questions buyers ask

▾Is CELOX Rapid Ribbon evidence-based standard?

Yes. CELOX Rapid Ribbon is a evidence-based standard hemostatic dressing, alongside CELOX Rapid and Celox Gauze. Combat Gauze remains the evidence-based hemostatic dressing of choice.1

▾How long do I hold pressure?

Medtrade labels the Ribbon for 60 seconds of firm pressure, and longer if bleeding persists; the TCCC Guidelines set at least 3 minutes for any hemostatic dressing.1,2 Follow the time your protocol sets, and keep pressure on until the bleeding has stopped and the packing is secured with a pressure bandage.

▾Ribbon or CELOX Rapid?

Same Chito-R™ technology, different width. The 1 in. Ribbon is built for narrow entry wounds — bullet, blast fragment and stab injuries; the 3 in. CELOX Rapid fills wider wounds.3

▾Tactical Dark Green or MARCH red?

Packaging only. MARCH red is the pack made for Safeguard Medical's RAMPART™ color-coded system, where red marks Massive Hemorrhage. The ribbon inside is the same; choose the pack that fits how your kit is organized.

▾How do I pack a wound wider than the Ribbon?

Fill it the same way — tightly to the source until the wound is filled above skin level.2 A wide, open cavity fills faster with a 3 in. gauze, so carry one alongside the Ribbon.

▾Is it safe for someone with a shellfish allergy?

The Ribbon contains chitosan from shellfish; Medtrade reports allergy studies show no adverse reaction to date.2 Shellfish-allergic volunteers tolerated a chitosan bandage without reaction in a challenge study.12 In a life-threatening bleed, do not withhold it over a reported allergy.

▾Does it work on someone taking blood thinners?

Medtrade states CELOX Rapid can be used on patients on anticoagulant therapy, because the chitosan gel does not rely on clotting factors.3 Pack and hold the same way, and reassess often for re-bleeding.

▾Does it get hot?

No. CELOX has been tested and shown to produce no increase in heat as blood clots.3

▾What if the bleeding doesn't stop?

Remove the packing and repack with a fresh dressing — the Ribbon again or another hemostatic.1 Adding gauze on top of a pack that has failed does not stop the bleeding underneath it.

▾Can I pack a chest or abdominal wound?

No. Packing is for wounds you can fill and compress — the groin, armpit, neck and limbs. Never pack into the chest or abdomen.2

▾How should I store it?

Sealed, dry and at ordinary room temperature; Medtrade's stability studies at 40 °C and 60 °C and through freeze-thaw cycles found no damage to product or packaging. The expiration date is printed on every pack.3

Package & specifications

▾In the package — one sterile dressing
  • 1× CELOX™ Rapid Ribbon hemostatic gauze, 1 in. × 5 ft (2.5 cm × 1.5 m), Z-folded
  • Gauze coated with Chito-R™ chitosan granules
  • Low-profile tear-open pack in your choice of Tactical Dark Green or MARCH red — MARCH red is Safeguard Medical's RAMPART™ color code
  • Sterile, single use. Pressure bandage and gloves sold separately.
▾Full specifications
Specification Detail
Manufacturer Medtrade Products Ltd, trading as CELOX™ Medical — Crewe, United Kingdom
Product CELOX™ Rapid Ribbon hemostatic Z-fold gauze, 1 in. × 5 ft
Manufacturer codes FG08839041 (Tactical Dark Green) · FG05839141 (MARCH red — Safeguard Medical's RAMPART™ color-coded packaging)
GTIN 15060206630762 (FG08839041) · 15060206630847 (FG05839141)
NSN 6510-01-623-9442
Active agent Chito-R™ activated chitosan granules on gauze
Mechanism Granules stick to wet tissue and form an adhesive gel that seals the wound; works independently of the clotting cascade (manufacturer)
Gauze 1 in. × 5 ft (2.5 cm × 1.5 m), Z-fold
Labeled compression 60 seconds of firm pressure; additional pressure until bleeding stops (manufacturer instructions)
Hypothermia Granules effective in blood down to 56 °F (13 °C) in laboratory testing (manufacturer)
Heat None
Sterility Sterile (irradiation), single use; do not use if the package is damaged
Storage Sealed, dry, at ambient room temperature; expiration date on every pack
FDA 510(k) K110386, CELOX Rapid Gauze (May 2011) — temporary external use to control moderate to severe bleeding
Allergen note Contains chitosan derived from shellfish
Warnings (manufacturer) Not for surgical use. Do not use in abdominal wounds or wounds not amenable to pressure. Do not apply over the eyes; if irritation occurs, flush with water for 5 minutes.
TCCC status evidence-based standard hemostatic dressing
▾References — 12 sources
  1. Committee on Tactical Combat Casualty Care. Tactical Combat Casualty Care (TCCC) Guidelines, 1 May 2026.
  2. CELOX™ Medical (Medtrade Products Ltd). CELOX™ Rapid Ribbon Hemostatic Z-Fold Gauze instructions for use, REF FG08839041 (artwork MTP-20-1815, issued 7 October 2020).
  3. CELOX™ Medical (Medtrade Products Ltd). CELOX™ Rapid Ribbon and CELOX™ Rapid product information; CELOX™ Technology — mode of action; CELOX™ frequently asked questions.
  4. U.S. Food and Drug Administration. 510(k) K110386, CELOX Rapid Gauze, Medtrade Products Ltd, cleared 10 May 2011.
  5. National Library of Medicine. AccessGUDID device records, CELOX RAPID Ribbon, model FG08839041 (DI 15060206630762), and CELOX Rapid Ribbon, model FG05839141 (DI 15060206630847).
  6. Defense Logistics Agency. Federal Logistics Information System record, NSN 6510-01-623-9442 (Celox Rapid Ribbon, 1 in. × 5 ft, Z-folded).
  7. Kunio NR, Riha GM, Watson KM, Differding JA, Schreiber MA, Watters JM. Chitosan based advanced hemostatic dressing is associated with decreased blood loss in a swine uncontrolled hemorrhage model. Am J Surg. 2013;205(5):505–510.
  8. Johnson D, Johnson M. The effects of QuikClot Combat Gauze and Celox Rapid on hemorrhage control. Am J Disaster Med. 2019;14(1):17–23.
  9. Gerling KA, Kersey AJ, Lauria AL, et al. Evaluation of novel hemostatic agents in a coagulopathic swine model of junctional hemorrhage. J Trauma Acute Care Surg. 2023;95(2S Suppl 1):S144–S151.
  10. Patterson K, Dagher AM, Lackie M, et al. User experience and hemostatic efficacy: comparative analysis of commercial agents in junctional and hepatic hemorrhage models. PLoS One. 2025;20(8):e0330696.
  11. Booms Z, Nguyen JQ, Smith B, et al. Assessment of hemostatic dressings for compressible wounds in a swine model simulating prolonged field care. Mil Med. 2026;191(5-6):e931–e937.
  12. Waibel KH, Haney B, Moore M, Whisman B, Gomez R. Safety of chitosan bandages in shellfish allergic patients. Mil Med. 2011;176(10):1153–1156.
Genuine CELOX™ — Medtrade Products Ltd
Sourced direct from the manufacturer or an authorized master distributor. Ships from MED-TAC International, South Florida, US of A — clinician-founded, veteran-led, SDVOSB-certified.
ADDITIONAL INFORMATION

Available Options:

  • MARCH Red Packaging
  • Tactical Dark Green
SPECS & MEASUREMENTS

Specifications coming soon. Contact us for detailed product information.

CLINICAL RATIONALE

Hemostatic Agents

1. Kaolin-Based Hemostatic Agents

(Examples: Combat Gauze, QuikClot EMS Rolled Gauze)

Clinical Rationale (Kaolin-Based):

Kaolin is an inorganic mineral hemostatic that accelerates the body’s natural clotting cascade by activating Factor XII (Hageman factor).
When applied to a bleeding wound, kaolin initiates the intrinsic coagulation pathway, resulting in rapid fibrin formation and stable clot development without generating heat.
Unlike older zeolite-based dressings, kaolin is completely non-exothermic, making it safe for extended wound packing and tissue contact.
It is a Committee on Tactical Combat Casualty Care (CoTCCC)–recommended dressing proven effective in both battlefield and civilian trauma care.

  • Triggers rapid clotting through Factor XII activation
  • No heat production — safe for direct tissue contact
  • Effective in hypothermic and coagulopathic patients
  • Durable gauze structure supports pressure dressings

2. Chitosan-Based Hemostatic Agents

(Examples: Celox Gauze, ChitoGauze, HemCon)

Clinical Rationale (Chitosan-Based):

Chitosan is a biopolymer derived from chitin, functioning through a positive-charge (cationic) mechanism that attracts negatively charged red blood cells and platelets.
This ionic reaction forms a gel-like clot that is independent of the body’s normal clotting factors, making it highly effective in patients with hypothermia or anticoagulant use.
Chitosan also has bacteriostatic properties that help reduce infection risk in contaminated wounds.
It is ideal for environments where traditional coagulation may be impaired.

  • Functions independently of natural clotting pathways
  • Effective in cold or anticoagulated patients
  • Forms an immediate mechanical seal on irregular wounds
  • Natural, biocompatible, and hypoallergenic

3. Cellulose-Based Hemostatic Agents (WoundClot)

(Examples: WoundClot Cellulose Gauze, WoundClot Battle Gauze)

Clinical Rationale (Cellulose-Based):

WoundClot represents a new generation of biosynthetic cellulose-based hemostats, engineered to form a hydrated, gelatinous matrix upon contact with blood.
This matrix absorbs fluid, stabilizes clot formation, and provides a scaffold for platelet and fibrin bonding.
Unlike other agents, WoundClot maintains its structure for hours, supporting sustained hemostasis under arterial or high-pressure bleeding.
It is completely bio-absorbable and non-allergenic, dissolving naturally within 5–7 days without removal.

  • Rapid gel-matrix formation supports durable clot structure
  • Fully bio-absorbable — no removal required
  • Effective for arterial, venous, and mixed bleeding
  • Allergy-safe, non-animal, and non-mineral composition

Clinical Summary

All hemostatic technologies—Kaolin, Chitosan, and Cellulose—share the goal of rapid external hemorrhage control, the leading preventable cause of trauma death.
Each mechanism is suited to specific medical and operational environments:

  • Kaolin: Dependable, non-exothermic, CoTCCC-recommended standard for general tactical use.
  • Chitosan: Ideal for anticoagulated, cold, or maritime conditions.
  • Cellulose (WoundClot): Advanced, bio-absorbable option for high-pressure or surgical-transition wounds.

Selection should be based on environment, casualty physiology, and evacuation timeline. Each mechanism offers unique advantages that complement modern tactical and civilian trauma protocols.

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