Tactical Medicine News Blog

Researchers at McMaster University in Ontario, Canada created engineered red blood cells to act as a new COVID-19 vaccine technology. The cell membranes have been studded with the SARS-CoV-2 spike protein, and in experiments the researchers have conducted in mice the cells can...

Researchers at MIT have created an oral mRNA delivery system that could provide an alternative to injectable mRNA vaccines. It could also enable RNA or DNA therapies that are intended to treat gastrointestinal diseases. mRNA has shown its therapeutic potential in spectacular f...

Researchers at Northwestern University have discovered naturally-occurring extracellular vesicles in the blood that contain the ACE2 protein, which is the cellular target of SARS-CoV-2. The vesicles act as a binding site for viral particles within the body, and prevent them fr...

Researchers at Northwestern University developed a nanoparticle delivery system for a common immunosuppressant drug that increases the potential of pancreatic islet transplantation as a viable long-term treatment for Type I diabetes. The technology targets the drug to act on t...

Researchers at the University of Pennsylvania School of Medicine have created a new coating for nanoparticles that can help to protect them from attacks by the immune system. The approach, which uses naturally occurring proteins that can inhibit the complement system, can sign...

Researchers at the Japan Advanced Institute of Science and Technology have developed a method to isolate intact lysosomes from cells. The technique is rapid and produces samples of high purity. Lysosomes are the garbage-disposal organelles within a cell, and they are involved ...

Researchers at Penn State working with collaborators have developed a nanomaterial that can ‘mop up’ chemotherapeutics in the bloodstream, helping to reduce off-target effects. The technology is intended for use in situations where a chemotherapeutic can be delivered precisely...

Genetic modification offers huge potential in treating a wide variety of conditions, but the devil is in the details. Previously explored methods to deliver genes into cells, such as using viral vectors, have been connected with safety issues. As such, the potential of gene th...

Researchers at the University of California San Diego developed a new delivery technique for mRNA. The method involves flu virus-inspired nanoparticles that can escape endosomes, the acidic vesicles that engulf and destroy materials that attempt to enter cells. The nanoparticl...

Delivering drugs to the brain remains a challenge due to the blood-brain barrier, a specialized endothelial layer that is highly selective in what it permits into the neural tissue beyond. At the University of Texas at Dallas, researchers have developed a technique that allows...