The Blog

Thanks for dropping by! We have curated an incredible collection of the best articles from the leading Emergency Medicine, Tactical Medicine, Prehospitial Medicine, Austere & Remote Medicine authors, as well as Survival Medicine gurus and many others!

We hope you find something of interested to you, please use the search bar on top to narrow down what you are looking for.

As always, all credit is given to the original author and origin publication.

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Tactical Medicine News

Tenecteplase vs Alteplase in Acute Ischemic Stroke

by Marco Torres
Jun 16, 2022
Background: At my shop we have changed wholesale to the use of tenecteplase over alteplase for acute ischemic stroke meeting criteria for thromboly...
Tactical Medicine News

MR CLEAN-NO IV: Endovascular Treatment for Stroke Compared to Alteplase Followed by Endovascular Treatment: No Difference, But Also Not Not Worse

Background: While the effects of stroke can be both debilitating and devastating, the benefit of certain treatments have not always been clear and ...
Tactical Medicine News

REBEL Cast Ep 105: Thrombolysis Before Endovascular Therapy for LVO Acute Ischemic Stroke

In this episode of REBEL Cast, Anand Swaminathan and I sit down to discuss the utility of thrombolysis prior to Endovascular therapy for LVO acute ...
Tactical Medicine News

Rebellion21: Stroke – Tiiii-ii-iiime is on Your Side, or is it? via George Willis, MD

In this 15-minute lecture from Rebellion in EM 2021, George Willis, MD discusses acute ischemic stroke and the evidence base for and against thromb...
Tactical Medicine News

Rebellion21: Alteplase for Stroke of Unknown Time of Onset

In this 9 minute video from day 2 of Rebellion in EM 2021, I go over the evidence for advanced imaging use in acute ischemic stroke of unknown time...
Tactical Medicine News

The STROKE-AF and PER DIEM Trials: Detection of Atrial Fibrillation After Stroke

Background: The mainstays for management of stroke include admission to a stroke center and management of modifiable risk factors.1,2,3 It is estim...
Tactical Medicine News

Should we Consider Endovascular Therapy for Acute Basilar Artery Occlusion?

Background: Acute basilary artery occlusion has a high morbidity and mortality.  Treatment strategies for acute basilar artery occlusion are rather...
Tactical Medicine News

Tenecteplase for Thrombolysis of AIS?

Background: Alteplase has been the accepted thrombolytic for acute ischemic stroke (AIS) for 25 years. However, recent data has emerged regarding t...
Tactical Medicine News

REBEL Cast Ep92: Alteplase for Stroke of Unknown Time of Onset?

Background: Intravenous alteplase is the current standard care for treatment of acute ischemic stroke (AIS) despite active debate on the research s...
Tactical Medicine News

The THALES Trial: Ticagrelor and Aspirin vs Aspirin Alone in Acute Ischemic Stroke or TIA

Background: The risk of a subsequent ischemic stroke in the first few months after an acute ischemic stroke or transient ischemic attack is approxi...
Tactical Medicine News

Thrombolysis in Acute Ischemic Stroke: Now We Have No Positive RCTs

Background: The scientific process in medicine is complicated. Obtaining high-quality data to guide management requires hypothesis formulation, dat...
Tactical Medicine News

REBEL Cast Ep84: Here We Go Again with Time is Brain

Background: Here we go again with another “Time is Brain,” acute ischemic stroke study.  The authors start out by saying that earlier administratio...
Tactical Medicine News

Extending Systemic Thrombolysis to 4.5 – 9 Hours and Wake-Up Strokes Using Perfusion Imaging: A Meta-Analysis

Background Information: The administration of alteplase (tPA) in acute ischemic stroke (AIS) continues to remain a highly debated topic. As hospita...
Tactical Medicine News

Extending the tPA Window to 4.5 – 9 Hours in Acute Ischemic Stroke (AIS)?

Background: No matter which side of the debate you sit on in regard to systemic thrombolysis in acute ischemic stroke (AIS), there is one truth: sy...
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