The VICTAS Trial: How Many More RCTs do we Need on the Metabolic Cocktail in Sepsis?
April 8, 2021
Background: Since the publication of the before and after Marik trial [1] published in 2016, there have been six randomized clinical trials trying to answer...
Marco Torres
Journal Jam 17 – Steroids for CAP and COVID Pneumonia
January 25, 2021
What are the indications for steroids in patients with pneumonia besides those with concurrent COPD exacerbations, ARDS or adrenal shock? What is the evidence for benefit...
Anton Helman
It’s Raining Steroids in COVID-19: REMAP-CAP, CoDEX, & CAPE COVID
September 5, 2020
Background: Over the past few years, corticosteroids have gained traction in the treatment of patients with ARDS and septic shock. Trials such as APROCCHSS and...
The ORANGES Trial: Why You Can’t Just Read the Abstract
July 16, 2020
Background: The cornerstones of sepsis management continues to include early identification, early appropriate empiric antibiotics, definitive source control, and vasopressors to support end organ perfusion....